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Clinical trials that are designed to help inform practice in the real world are called pragmatic trials. They are often described as a focus on the practical aspects of designing a study which include the recruitment process and consent, adhering and the use routinely available equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which utilized a variety of investigators and participants from different geographic areas. This kind of heterogeneity is essential for practical trials to be valid and helps to reduce bias in the results. A high degree of heterogeneity, however can result in problems with the trial design.

Pragmatic Play is also a major player on the live casino market, providing an array of table games like as Blackjack and Roulette in a variety of versions. The live studios of Pragmatic Play's offices in Romania and Malta provide customers with an authentic gambling experience, and a wide variety of betting options via virtual. The company has also developed various interactive games to make online gambling fun. Some of these shows feature live hosts, whereas others are hosted by famous personalities from the industry.

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The majority of Pragmatic Play slot games feature traditional themes as well as modern graphics, which makes them popular for both new and experienced players. Many of them have progressive jackpots and come with multiple paylines and bonus rounds. They are also not particularly volatile, so you can expect to have a long-lasting gaming session with them.

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The purpose of pragmatic trials is to replicate real-life scenarios and gain the highest level of validity externally. They are usually commissioned by policy makers and 프라그마틱 정품 확인법 practitioners to aid in their decision-making. They also provide a useful method to determine the cause-effect relationship between the intervention and its effects. However, they shouldn't be used to substitute for explanatory studies.

The concept of pragmatism is controversial, and there are questions regarding whether pragmatic trials could replace tests for explanations or if they should serve as an alternative to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which prove the validity of a clinical or physiological hypothesis, and pragmatic trials, which guide policy and practice decisions. They also suggested a framework for pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a practical trial that include the recruitment process, the design and implementation of the intervention, as well as monitoring.

The number of pragmatic trials is increasing. A recent Medline search using the keywords naturalistic and pragmatic, limited to controlled trials randomized to control (RCTs) produced 34 articles, shown in red in Figure 2. This is a sign that the health sciences community is becoming increasingly sensitized to the subject of pragmatism. However, it is important to remember that the majority of these studies were conducted in primary care settings.